Does blood sugar get better when taking vitamin C?

Does blood sugar get better when taking vitamin C?

Some sugar friends told me that recently taking vitamin C, blood sugar is much better, fasting blood sugar is 6 o’clock.

There are studies that have looked at the effect of taking vitamin C on blood sugar and found that fasting blood sugar and insulin resistance have improved.

However, another sugar friend said that her blood sugar may be falsely lowered, which is a interference with the detection method by vitamin C.

This sugar-friendly professional!

Does vitamin C really interfere with blood sugar test results?

After checking the data, I saw that the 2011 version of the Chinese blood glucose monitoring clinical application guidelines mentioned that vitamin C may falsely increase the blood glucose measurement value, but this sentence was deleted in the 2015 new version of the guidelines.

The new guidelines only mention that the common substances that interfere with blood glucose detection are: acetaminophen, vitamin C, salicylic acid, uric acid, bilirubin, triglycerides and other endogenous and exogenous substances. When there are a lot of interfering substances in the blood, there will be a certain deviation in blood sugar levels.

Vitamin C, what kind of false changes in blood sugar results will occur, is it higher or lower?

A doctor engaged in laboratory research in Nanjing gave a clear answer: the effect of vitamin C on blood glucose test results depends on the detection method of the blood glucose meter.

His findings were published in the International Journal of Laboratory Medicine in 2017.

The study found that:

Hexokinase method: not interfered with vitamin C, no matter how high the concentration of vitamin C, there is no obvious interference with blood sugar, and the deviation is between -0.44% ~ 0.89%.

Glucose oxidase method: when the blood vitamin C concentration exceeds 78mg/L, the blood glucose detection is falsely reduced, and the higher the vitamin C concentration, the greater the deviation.

Glucose reductase electrode method: when the blood vitamin C concentration exceeds 78mg/L, the blood glucose detection is falsely increased, and the higher the vitamin C concentration, the greater the deviation.

The reasons for this interference are:

Vitamin C has strong reducibility and can inhibit the oxidation reaction in glucose oxidase, resulting in a decrease in results;

It can also promote the reduction reaction in glucose reductase method, so that the results are high.

Vitamin C is an essential nutrient for the human body, and the concentration of vitamin C in fasting plasma of healthy people is 50~70μmol/L. When the clinical intravenous infusion of vitamin C reaches a certain concentration, the strong reducing ability of vitamin C will seriously interfere with a variety of blood glucose measurement methods, and it is necessary to use hexokinase method to detect blood glucose levels as much as possible.

If sugar friends take vitamin C, it may have a similar effect on blood sugar measurements.

Hexokinase is usually used with a biochemical analyzer.

The blood glucose meters using glucose oxidase method on the market include Johnson & Johnson Stable Blood Glucose Meter, Abbott Antol Blood Glucose Meter, Bayer Ester 2nd Generation of Germany, Sugar Doctor, Sannuo Anwen, Yicheng and so on.

The advantage of the detection method is that it is highly specific and is not affected by other sugars such as xylose, maltose, galactose.

The disadvantage is that it is easily interfered with by oxygen, and it is necessary to avoid long-term contact with oxygen, and the open test strip is used within 3 months.

And: When taking large amounts of vitamin C, false test results can occur.

There are few blood glucose meters that use the glucose reductase method, and there is a microblood glucose meter in Kyoto, Japan.

When vitamin C is taken in large quantities, false high test results occur.

The glucose meters on the market using glucose dehydrogenase method include Abbott Riamptan, Anto, Roche Superior, Roccan Full Vitality, American Huihao Excellent Measurement Type, Sannuojin Stable Type, etc.

The advantages of the detection method are: it is not disturbed by oxygen molecules in the blood, not disturbed by oxygen in the air, and the validity period of the test strip is not affected by the opening time.

Disadvantages: less specificity, may react with other sugars such as maltose, xylose or galactose.

There is no research data on blood sugar changes when taking vitamin C, and from the detection principle, there are both reduction reactions and oxidation reactions.

It seems that in addition to monitoring blood sugar with a blood glucose meter, sugar friends should also remember to regularly check glycated hemoglobin to assess their blood sugar control!

Because, the improvement in blood sugar on your fingertips may not be real.

Product Recommendation: 80g Vitamin C Fruit Candy